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# ChromFound
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ChromFound is a foundation model for scATAC-seq that leverages a hybrid architecture and genome-aware tokenization to capture genome-wide regulatory dynamics from chromatin accessibility profiles. Trained on 1.97 million cells spanning 30 tissues and 6 disease contexts, it delivers strong zero-shot and transfer performance across diverse tasks, providing a powerful framework for decoding enhancer–gene regulation and noncoding variant functions.
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### v1.0.0 (2025-10-16)
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- Initial release
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- Support for basic cell embedding and cell type annotation functionality
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license: apache-2.0
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# ChromFound
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ChromFound is a foundation model for scATAC-seq that leverages a hybrid architecture and genome-aware tokenization to capture genome-wide regulatory dynamics from chromatin accessibility profiles. Trained on 1.97 million cells spanning 30 tissues and 6 disease contexts, it delivers strong zero-shot and transfer performance across diverse tasks, providing a powerful framework for decoding enhancer–gene regulation and noncoding variant functions.
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### v1.0.0 (2025-10-16)
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- Initial release
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- Support for basic cell embedding and cell type annotation functionality
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- update README.md
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